
Untreated bipolar disorder can last for months. Once the disorder is activated, it typically persists, and untreated first episodes rarely remain dormant.
The first step in treating bipolar disorder is getting the correct diagnosis, which requires an extensive patient’s interview, ideally also involving close relatives. For the psychiatrist, it’s important to know not only the current symptoms but also past mood swings and the family history. Early diagnosis is crucial for a positive therapy outcome.
The fewer episodes a patient has had before starting treatment, the better they usually respond. Early treatment can also prevent the disorder from becoming chronic, which can have serious health and social consequences.
For diagnosis, contact our bipolar disorder specialist, Dr. Kowal
Call CHMCDiagnostic Procedures of Bipolar Disorder
Bipolar disorder should be assessed by an experienced psychiatrist. Diagnosing bipolar disorder can be difficult, especially when the illness begins with a depressive episode. At first, it may appear to be a unipolar depression. However, some signs can suggest bipolar disorder. Patients with bipolar depression often experience stronger loss of energy, increased need for sleep, and increased appetite. The first depressive episode also frequently occurs at a younger age, often during adolescence or early adulthood.
On the other hand, the patient and his family may overlook hypomania symptoms. If depression appears first in the course of the illness, it’s unclear whether it is unipolar (“one-sided”) or bipolar depression. On the other side, symptoms of hypomania can also be overlooked by the patient and his family.
An in-depth investigation is also important because bipolar disorder can resemble other serious psychiatric conditions. Diagnoses such as schizophrenia, schizoaffective disorder, ADHD, or depression can be misdiagnosed as bipolar disorder.

Steps in Bipolar Disorder Assessment
Clinical interview
The diagnosis of bipolar disorder requires a detailed psychiatric and medical assessment starting with an extensive interview with the patient and, if possible, with family members. This is important because many patients do not fully recognize past hypomanic episodes or changes in mood and behavior.
Physical Examination
In bipolar disorder, a physical examination is not used to directly diagnose the illness. Bipolar disorder is mainly diagnosed through psychiatric assessment and the patient’s symptoms. However, a medical check-up is very important to rule out physical illnesses that can cause mood changes and to make sure that psychiatric medication can be used safely.
The examination helps doctors exclude medical conditions that may look similar to bipolar disorder, such as thyroid problems or neurological diseases. It also provides important baseline values before starting treatment.
Blood Pressure, Pulse, and Weight
Doctors usually begin with a general health check. Blood pressure and pulse are measured because some psychiatric medications can affect the heart and circulation.
Weight and body mass index (BMI) are also recorded. Certain mood stabilizers and antipsychotic medications may increase appetite and lead to weight gain.
Neurological Examination
Doctors may test reflexes, coordination, walking, and muscle control. This helps rule out neurological illnesses that can sometimes cause psychiatric symptoms.
Conditions such as Parkinson’s disease, multiple sclerosis, epilepsy, or early dementia may sometimes imitate mood disorders.
Blood and Urine Tests
Thyroid Hormones
Blood tests for thyroid hormones, including TSH, fT3, and fT4, are very important. Thyroid imbalance can cause mood swings that resemble bipolar disorder.
Liver and Kidney Function
Liver and kidney tests are necessary before starting medications such as lithium, valproate, or carbamazepine. These medications are processed through the liver or kidneys and require regular monitoring.
Additional Diagnostic Tests
Those tests can help rule out other contributing factors, especially heart problems and physical illnesses such as epilepsy, brain tumors, thyroid disorders, migraines, dementia, or Parkinson’s disease.
ECG (Electrocardiogram)
An ECG checks the heart rhythm. Some psychiatric medications can affect electrical activity in the heart, so doctors may perform this test before starting treatment.
Brain Imaging (MRI or CT Scan)
MRI or CT scans of the brain are usually only needed in special situations, such as a first episode later in life or unusual symptoms. These scans help exclude strokes, tumors, or other structural brain diseases.
EEG (Electroencephalogram)
An EEG records brain activity and may be used to rule out epilepsy, especially temporal lobe epilepsy, which can sometimes cause strong mood changes.
Why Bipolar Disorder Is Often Misdiagnosed
Bipolar disorder is one of the most frequently misdiagnosed psychiatric conditions. Many people first seek professional help during a depressive episode, when symptoms such as sadness, loss of interest, fatigue, and hopelessness are most prominent. If previous episodes of mania or hypomania are not recognised or discussed, bipolar disorder may be mistaken for recurrent depression. As a result, patients may receive treatment that improves depressive symptoms but does not address the underlying mood disorder.
Bipolar disorder can also resemble ADHD. During manic or hypomanic episodes, patients often experience distractibility, racing thoughts, increased activity, and difficulty concentrating. Unlike ADHD, however, these symptoms occur in distinct mood episodes and are separated by periods of normal functioning. ADHD usually begins in childhood and causes persistent attention problems rather than episodic mood changes.
Another condition that may be confused with bipolar disorder is borderline personality disorder. Both disorders can involve mood instability, impulsive behaviour, and relationship difficulties. However, mood changes in borderline personality disorder are usually triggered by interpersonal conflicts and often last for hours. In bipolar disorder, manic and depressive episodes typically develop independently of external events and continue for days or weeks.
Anxiety disorders are also common in people with bipolar disorder and may even be the main reason they seek treatment. Symptoms such as restlessness, sleep disturbances, excessive worrying, and poor concentration can overlap with bipolar disorder. In many patients, anxiety exists alongside bipolar disorder rather than replacing the diagnosis.
Because several psychiatric disorders share similar symptoms, an accurate diagnosis requires a comprehensive psychiatric assessment. A detailed evaluation of previous mood episodes, family history, medical conditions, and symptom patterns allows the psychiatrist to distinguish bipolar disorder from other conditions and develop the most appropriate treatment plan.
Diagnosis of Bipolar Disorder at CHMC in Dubai. Conclusion
An accurate diagnosis is the foundation of successful bipolar disorder treatment. Because bipolar disorder often resembles depression, anxiety disorders, ADHD, or other psychiatric conditions, a comprehensive psychiatric assessment is essential. Identifying the correct diagnosis allows the psychiatrist to develop an effective treatment plan and reduce the risk of future mood episodes.
If you experience recurrent depression, episodes of unusually elevated mood, decreased need for sleep, impulsive behaviour, or significant mood swings, do not ignore these symptoms. Early diagnosis and appropriate treatment can improve long-term outcomes, prevent unnecessary suffering, and help you maintain a stable and fulfilling life.
At CHMC German Clinic for Psychiatry and Psychology in Dubai, we provide comprehensive assessment, accurate diagnosis, and evidence-based treatment for bipolar disorder. If you are concerned that you or a loved one may have bipolar disorder, we encourage you to arrange a psychiatric consultation. Early intervention offers the best opportunity for long-term mood stability and recovery.
Call CHMCFAQs About the Diagnosis of Bipolar Disorder
Can bipolar disorder be diagnosed with a blood test?
No. There is currently no blood test that can diagnose bipolar disorder. However, blood tests are often performed to exclude medical conditions, such as thyroid disorders or vitamin deficiencies, that can cause symptoms similar to bipolar disorder.
Can bipolar disorder be diagnosed with brain scans?
No. Brain scans such as CT or MRI cannot confirm bipolar disorder. These investigations may be recommended if a neurological condition is suspected, but the diagnosis is based primarily on a comprehensive psychiatric assessment.
How long does a bipolar disorder assessment take?
A thorough bipolar disorder assessment usually takes between 60 and 90 minutes. The psychiatrist reviews current symptoms, previous mood episodes, medical history, family history, and any previous treatments before making a diagnosis.
Can bipolar disorder be mistaken for ADHD?
Yes. Both conditions can cause distractibility, impulsivity, restlessness, and poor concentration. The key difference is that ADHD symptoms are usually lifelong, while bipolar symptoms occur in distinct episodes of mania, hypomania, or depression.
Can bipolar disorder appear later in life?
Yes. Although bipolar disorder most commonly begins during adolescence or early adulthood, it can also develop later in life. New mood symptoms appearing in older adults require careful psychiatric and medical evaluation to exclude other medical or neurological conditions.
Can bipolar disorder be mistaken for depression?
Yes. Many patients first seek help during a depressive episode. If previous episodes of mania or hypomania are not recognised, bipolar disorder may initially be diagnosed as recurrent depression. This is one of the most common reasons for delayed diagnosis.
How is bipolar disorder diagnosed?
Bipolar disorder is diagnosed through a detailed psychiatric assessment. The psychiatrist evaluates mood symptoms, previous episodes of mania, hypomania and depression, family history, medical conditions, and the overall pattern of the illness. There is no single laboratory test that confirms the diagnosis.
Why is an accurate diagnosis so important?
An accurate diagnosis is essential because bipolar disorder requires different treatment from depression, anxiety disorders, or ADHD. Correct diagnosis allows the psychiatrist to develop an effective treatment plan and reduces the risk of future mood episodes.
Can family members help with the diagnosis?
Yes. Family members can often provide valuable information about changes in mood, behaviour, sleep, and daily functioning. This is particularly helpful if the patient has limited insight during manic or hypomanic episodes.
What should I do if I think I have bipolar disorder?
If you experience recurrent depression, unusually elevated mood, decreased need for sleep, impulsive behaviour, or significant mood swings, you should arrange a comprehensive psychiatric assessment. Early diagnosis and treatment can prevent more severe episodes and improve long-term quality of life.
Read More About Bipolar Disorder
- Treatment for Bipolar Disorder
- Symptoms of Bipolar Disorder
- Diagnosis of Bipolar Disorder
- Self-Test for Bipolar Disorder
- Psychiatrist for Bipolar Disorder
- Bipolar Disorder in Pregnancy
- Medication for Bipolar Disorder
- Psychotherapy for Bipolar Disorder
- Causes of Bipolar Disorder
- Bipolar I vs Bipolar II Disorder
- What is Rapid Cycling?
- Bipolar Disorder and Sleep
- Living with Bipolar Disorder
- Relationships, Family, Everyday Life with BD
- Long Term Recovery & Quality of Life with BD
- Family Support in Bipolar Disorder
- What is Mania and Hypomania?
- Cyclothymic Disorder
- History of Bipolar Disorder
- CANMAT Guidelines for Bipolar Disorder
- Mood Stabilizers for Bipolar Disorder
- Lithium for Bipolar Disorder
Medically reviewed by Dr. Gregor Kowal

DR. GREGOR KOWAL
Dr. Gregor Kowal is a German-certified consultant in Psychiatry and Psychotherapy. Since 2010, Dr. Kowal has been the Medical Director of CHMC, a psychiatric clinic located in Dubai. Dr. Kowal graduated from the prestigious University of Heidelberg. After completing his specialty training, he held leadership and teaching positions, serving as Head of Department and later as Medical Director at renowned psychiatric hospitals across Germany. In addition to his expertise in psychiatry, Dr. Kowal is trained as a psychotherapist with a foundation in psychoanalytical psychotherapy.
